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Cellular iron is a vital component of life
Cellular iron is a vital component of life
Iron is essential for many key cellular cellular processes, including respiration, DNA synthesis and oxygen transport. In excess, cellular iron catalyzes the generation of free radicals that damage protein, DNA and lipids, whereas cellular iron deficiency impairs cellular proliferation. Recently, we looked at iron dysregulation following treatment with the chemotherapeutic drug doxorubicin.